Enterprise

Rent A Car and Drive From New York City to Buffalo

Are you looking to take a road trip? A rental car from your local neighborhood Enterprise location might be the best option for your travel! Enterprise offers quick, convenient travel options so you can get on the road faster. With so many styles and options available, you’re sure to find the perfect rental car for your travels.  

Drive time: approx. 6 hours (Driving Directions)

Distance: approx. 374 miles

Benefits of Renting a Car

  • Reduce wear-and-tear and/or mileage on your own vehicle
  • Choose from a variety of rental cars – like compacts, minivans or luxury SUVs – to fit your group’s needs
  • Select a style with extra cargo space – perfect for camping gear, hiking equipment or that last-minute RSVP
  • Enjoy add-ons such as car seats, GPS/navigational systems, ski racks and more 

Popular Road Trip Cars

Take your pick from one of these classic road trip car options.

SUVs

Our SUVs offer flexibility with seating capacity, power, and luggage room. Find the ideal SUV for your next weekend family trip or exploring the countryside.

Rent an SUV

Trucks

Looking to haul large items for DIY projects or going on a weekend retreat? A pickup truck has space, power and durability ideal for your project or trip.

Rent a Truck

Vans

Need extra room for people, luggage, or cargo or both? Our minivans and passenger vans can seat up to 7 and 15 people and are great for family vacations or large groups.

Rent a Van

New York Drives and Road Trips

Map - Drive from New York to Boston

Drive from New York to Boston

Hop in the car and drive from New York to Boston. Discover interesting stops along short drive from the Big Apple to Beantown.

Rent a Car & Drive From New York City to Nantucket

Drive From New York City to Nantucket

Looking to go from New York City to Nantucket? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Drive from New York City to Buffalo

Drive from New York City to Buffalo

Looking to go from New York City to Buffalo? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - Drive from New York to Niagara Falls in 5-days

Road Trip from New York to Niagara Falls in 5-days

Drive from New York City to Niagara Falls using this 5 day itinerary. Explore towns throughout upstate New York including Syracuse, Albany and more.

Drive from New York City to Philadelphia

Drive from New York City to Philadelphia

Looking to go from New York City to Philadelphia? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - Drive from New York to Washington DC

Drive from New York to Washington DC

Discover plenty of American History by driving from New York to Washington, D.C. This day trip will take you through Philadelphia and Baltimore.

Map - Boston to NYC

Road Trip from Boston to New York City

Explore Bristol, New Haven and more as you drive from Boston to New York City using this weekend trip itinerary.

Map - Driving from Washington DC to NYC

Driving from Washington DC to NYC

Explore the amazing sights you are bound to find along the East Coast on your drive from our nation's capital to NYC.

Rent a Car & Drive From New York City to The Hamptons

Drive From New York City to The Hamptons

Looking to go from New York City to The Hamptons? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - Drive from New York to Florida in 2-days

Road Trip from New York to Florida in 2-days

Looking to take a trip to one of Florida's spectacular white sand beaches? See our favorite stops on this 2-day trip from NYC.

Beaches Near New York City

Beaches Near New York City

Looking for the nearest beaches to New York City? Our neighborhood locations are open and ready to serve you with curbside pickup and enhanced vehicle cleaning procedures.

Rent a Car & Drive From New York City to Lake Placid

Drive From New York City to Lake Placid

Looking to go from New York City to Lake Placid? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - Drive from New York to Niagara Falls in 3-days

Road Trip from New York to Niagara Falls in 3-days

Escape the city for the weekend and explore the numerous waterfalls along your trip from New York City to Niagara Falls.

Drive from New York City to Cape Cod

Drive from New York City to Cape Cod

Looking to go from New York City to Cape Cod? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Rent a Car & Drive From New York City to Bar Harbor

Drive From New York City to Bar Harbor

Looking to go from New York City to Bar Harbor? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - Drive from New York to Florida in 4-days

Road Trip from New York to Florida in 4-days

Looking to take a trip to one of Florida's spectacular white sand beaches? See our favorite itineraries and enjoy the journey as much as the destination!

Driving Resources

Camping Checklists

The Enterprise App

Our iOS and Android apps make it easier than ever to manage reservations on the go.

Learn More & Download

Camping Checklists

Meet the Fleet

With so many styles and options available, you're sure to find the perfect rental for your travels.

View All Vehicles

Camping Checklists

Car Rental FAQs

Check out our FAQs for information on hours of operation, upcoming and existing reservations and more. 

View FAQs